CLC2D Polyclonal Antibody, 100ul Immunology disease:A chromosomal aberration involving FOXO3

disease:A chromosomal aberration involving FOXO3 is found in secondary acute leukemias

The protein encoded by RHOH is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes

The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein

The encoded preproprotein is proteolytically processed by furin to generate the mature receptor

Required for efficient interaction with E1A

CLC2D Polyclonal Antibody, 100ul Immunology disease:A chromosomal aberration involving FOXO3This gene encodes a member of the natural killer cell receptor C type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N terminus as well as the C type lectin like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene.