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Tropomyosin Alpha Polyclonal Antibody, 50ul Hepatocytes Expression of this gene is

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Tropomyosin Alpha Polyclonal Antibody, 50ul Hepatocytes Expression of this gene isTPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non muscle cells. Tropomyosin is composed of two alpha helical chains arranged as a coiled coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The tropomyosin alpha 1 chain is one type of alpha

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Description

Expression of this gene is downregulated during tumor progression

Multiple alternatively spliced variants encoding different isoforms have been described

The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction

Melnick-Needles syndrome (MNS)

This gene encodes a nicotinic acetylcholine receptor| which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses

Tropomyosin Alpha Polyclonal Antibody, 50ul Hepatocytes Expression of this gene isTPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non muscle cells. Tropomyosin is composed of two alpha helical chains arranged as a coiled coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The tropomyosin alpha 1 chain is one type of alpha

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