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TMPO Polyclonal Antibody, 50ul Custom Peptide Synthesis The function of the protein

SKU: 1390405402

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TMPO Polyclonal Antibody, 50ul Custom Peptide Synthesis The function of the proteinThe protein encoded by TMPO (thymopoietin) resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in TMPO are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for

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Description

The function of the protein encoded by this gene is not known

53BP1 was isolated from H258 cells and is expressed in Jurkat cells in both the cytoplasm and the nucleus

PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes

During T-cell activation| this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site| suggesting a negative regulatory role in adaptive immune response

Four alternatively spliced transcript variants encoding distinct isoforms have been described

TMPO Polyclonal Antibody, 50ul Custom Peptide Synthesis The function of the proteinThe protein encoded by TMPO (thymopoietin) resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in TMPO are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for

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